>>292 A diet deficient in the amino acid methionine has previously been shown to extend lifespan in several stocks of inbred rats. https://pubmed.ncbi.nlm.nih.gov/15924568/
…In particular, it was shown that restriction of a single amino acid, methionine, can mimic the effects of DR and extend lifespan in various model organisms.
…In this regard, the most successful case has been the use of methionine restriction (MR) diet. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008916/