Table 1: Contraindications for sibutramine therapy include:1
• History of coronary artery disease, congestive heart failure, arrhythmias or cerebrovascular disease (stroke or transient ischemic attack) • Inadequately controlled (> 145/90 mm Hg) or unstable hypertension • Psychiatric illness • Concomitant use of centrally acting drugs (e.g., antidepressants and antipsychotics) or herbal remedies (e.g., St John’s Wort) for the treatment of psychiatric disorders; monoamine oxidase inhibitors; or other centrally acting weight-reducing agents • History of, or presence of, a major eating disorder such as anorexia nervosa or bulimia nervosa • Hypersensitivity to sibutramine or to any ingredient in the formulation or component of the container
> Contraindications for sibutramine > • Psychiatric illness
