ソース INSERM Researchers in France Raise an Uncomfortable Question about ADE & COVID-19 Vaccines https://trialsitenews.com/inserm-researchers-in-france-raise-an-uncomfortable-question-about-ade-covid-19-vaccines/ Recently, INSERM researchers produced a peer review assessment with disturbing implications for those who keep an open mind to what could occur as the pandemic and mass vaccination programs unfold worldwide. （中略）Moreover, they indicate that there is now a risk with current vaccines associated with ADE of delta variants, while finally, vaccine formulations should preclude ADE epitope.
フランスの研究チームは、Journal of Infection誌に最近発表された論文（2021年8月10日）において、現行のワクチンではデルタ株に対してADE（抗体依存性感染増強） の作用を強めるリスクがあることを指摘し、潜在的なADEリスクに対してより安全性の高い次世代ワクチンを開発していくことを考えるべきだと提言している。 Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination? https://pubmed.ncbi.nlm.nih.gov/34384810/ ＞However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies ＞display a strikingly increased affinity. Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence ＞ (either mRNA or viral vectors). Under these circumstances, second generation vaccines with spike protein formulations lacking structurally-conserved ＞ADE-related epitopes should be considered.
